[ RESOURCE CENTER ]
Compliance Resources & Regulatory References
This resource center provides trusted regulatory references, practical compliance manuals, and readiness tools to support DEA-registered organizations. All materials are designed to help strengthen recordkeeping, security, due diligence, and inspection preparedness.
[ USEFUL MANUALS ]
DEA Compliance Manuals & Official Guidance
The official DEA final rule outlining Controlled Substances Ordering System requirements and compliance obligations.
A practical guide for registrants using CSOS 2.0 for electronic ordering of Schedule II controlled substances.
Comprehensive guidance for opioid treatment programs on DEA registration, recordkeeping, security, and dispensing requirements.
Detailed operational and compliance standards specific to DEA-registered Narcotic Treatment Programs.
Authoritative reference for pharmacists covering controlled substance dispensing, recordkeeping, inventory, and security requirements.
Essential guidance for prescribers on lawful prescribing, dispensing, documentation, and diversion prevention.
Compliance requirements for researchers handling controlled substances in approved research protocols.
Regulatory guidance for registrants handling List I and List II chemicals, including import, export, storage, and reporting.
[ DEA Guidance ]
Explore our core compliance resources
Practical access to official DEA guidance and federal regulations that support lawful handling of controlled substances and regulated chemicals.
DEA Diversion Control
Official enforcement guidance from the DEA Office of Diversion Control. Access policies, compliance notices, registrant guidance, and diversion prevention resources directly from the DEA.
Federal Regulations (21 CFR)
Current Title 21 Code of Federal Regulations governing controlled substances. Stay aligned with federally enforced rules covering prescribing, dispensing, recordkeeping, and security requirements.
Controlled Substances Act (CSA)
The legal foundation for DEA registration and compliance. Review the statutory requirements that define controlled substances, registrant responsibilities, and enforcement authority.
CSOS (Electronic Ordering)
Secure electronic ordering for Schedule II controlled substances. Learn about CSOS enrollment, certificates, and compliance requirements for electronic controlled substance ordering
